Pasquotank County decreased in size in 1729 when Tyrrell County was created, and in 1777 when Camden County was created.

Its population grew from 5,497 in 1790 to 40,661 in 2010.

Click on the maps below to peruse the known towns and villages that came and went over the past three centuries or so - a few cannot be located since they do not show up on available maps of NC.