Established in 1850 by a group of locally prominent landowners, Carolina Female College was placed under the auspices of the Methodist Church. A sum of $20,000 went toward construction of the college building. Young women aged ten (10) to twenty (20), many of them daughters of ministers, from as far away as Mississippi attended. The first president was the Reverend Alexander B. Smith of Anson County. Classes were suspended from 1862 to 1864 due to an outbreak of typhoid fever and the American Civil War.

The school closed in 1867 at which time stockholders placed the property in the hand of the South Carolina Methodist Episcopal Conference. Residents of the Palmetto State, however, evinced little interest in the institution. Local secondary school classes were held in the old building until about 1885. For some years thereafter it served as an apartment house but by the mid-twentieth century the structure was in state of decay and was demolished in the 1950s.

The above write-up (with edits) was provided by the North Carolina Highway Marker program. Click Here to read and to view their sources.